PICkit3 can't see PIC18F46K80, questions voltage, gets zero for Target Device ID... (SpokaneNexus)

We've been using PIC24F's for several years now, with a PICkit3 that works perfectly. We've done a new board that uses our first PIC18F running on 5V. When we plug in the PICkit3, we get a series of problems. There are lots of threads that raise this ques..