IDE 5.50 - PICkit3 - Could not connect to tool hardware (domble)

MPLab 5.50, PIC18F24K22, XC8 2.20, PIC18F-K_DPF 1.4.87, PICkit3.In MPLab,BUILD SUCCESSFUL (total time: 119ms)
Loading code from C:/Proj/.../dist/default/production/...X.production.hex...
Program loaded with pack,PIC18F-K_DFP,1.4.87,Microchip